2025 ASCP Blood Banking Specialist Practice Exam – Complete Test Prep

The most common infectious adverse effect of blood transfusion is bacterial contamination. This is particularly significant because transfusion-related bacterial infections can lead to severe complications and even high mortality rates. Bacterial contamination can occur during the collection, processing, or storage of blood products, with organisms often introduced from the skin or through the use of inadequately checked equipment.

When blood components, such as platelets, which are usually stored at room temperature, become contaminated, bacteria can proliferate rapidly. This reflects the critical importance of maintaining strict aseptic techniques throughout the blood transfusion process and monitoring for signs of infection post-transfusion.

Other options listed may be associated with adverse effects from blood transfusions but are not as frequently linked directly to infectious processes as bacterial contamination is. For instance, hepatitis is more strongly tied to viral transmission from transfusions, which is less common due to rigorous screening practices now in place. Additionally, urticaria is a type of allergic reaction rather than an infectious adverse effect. Hemolytic transfusion reactions result from immune responses rather than infection.

Understanding these concepts is crucial for ensuring patient safety and effectively managing transfusion risks in clinical settings.